Unlike many programs in innovation and entrepreneurship, the E4B Program seeks to develop skills in entrepreneurial thinking that can be applied whether you continue in academia, work in industry, form a nonprofit venture, or create a new startup!

Program Elements


The E4B Training Program consists of nine nanocourses, with each focused on one aspect of the innovation and entrepreneurship process.

Nanocourses consist of lecture videos, resources for additional learning, and optional activities to help you master the skills taught in the videos.

1. Introduction to the World of Biomedical I&E
Introduces the world of biomedical innovation and entrepreneurship. Topics covered include the link between ideas and intellectual property, innovating within institutions, unique challenges for life science innovators, iterative de-risking, the “fast fail,” and funding.

2. Survive and Thrive as an Innovator
Improve your psychological well-being, including self-esteem, gratitude, the mind-body connection, physical activity, emotional intelligence, and resilience.

3. Building Effective Teams
Identify the skills and capabilities needed on a team, how to recruit them to your cause, and ensure that they will work together to bring your vision to fruition.

4. Diversity, Equity, and Inclusion in I&E
Learn about the four Ps of diversity, equity and inclusion – Purpose, People, Place, and Practice – and the strategies you can use to create a diverse, equitable, and inclusive organization.

5. Identifying Opportunities for Innovation
Learn how to identify opportunities for innovation by identifying problems, rapidly generating potential solutions, and employing strategies to increase their value and viability.

6. Validating Your Innovation
Build on the ideas generated in the Identifying Opportunities nanocourse to validate (or invalidate) the underlying assumptions associated with your innovation.

7. Fishing for Customers
Expands upon Validating Your Innovation, and provides additional tools and guidance to help you identify, engage with, and secure paying customers.

8. Ethics in Biomedical I&E
Learn to face the unique challenges biomedical innovators face that are not easily resolved through traditional business or medical ethical frameworks.

9. Selling Your Innovation
Learn how to further refine your vision of the future and recruit others to believe in and champion your cause.

Capstone Project & Live Virtual Pitch Sessions

Your work in E4B builds towards a capstone project composed of three deliverables for a new innovation: an executive summary, a pitch deck, and conducting a live virtual pitch presentation over Zoom.

Capstone projects are completed in teams of about four people and must be completed to earn your certificate.

You will work on deliverables throughout the program, and submit them for review to your mentors every few weeks. As with all things I&E, these are living documents and will be updated throughout the program.

Watch Salentra Biosciences’ fall 2020 pitch session


E4B teams are assigned two (or more) mentors who help them complete their capstone project.

Mentors are assigned based on a team’s innovation, and agree to be available for team interactions for up to 30 minutes each week.

Mentors come from GE Healthcare, Washington University, Lilly, Pfizer, BioGenerator, Bacterioscan, and over a dozen other academic, industry, and venture capital partners.

Boot Camp

Due to the COVID-19 pandemic, all in-person events are on hold.

Held semi-annually, the E4B Boot Camp provides an opportunity for trainees and mentors to meet in-person at Washington University in St. Louis.

Activities include talks and pitches from experienced entrepreneurs, opportunities to network with team members and mentors, and participating in a team pitch challenge.

Fall 2019 Events

  • Keynote speaker: Jeff Hersh, MD, PhD Chief Medical Officer, GE Healthcare “Translating Science into Impact through an Entrepreneurial Mindset”
  • Pitch demo & Q&A: Zach Vesoulis, MD, MSCI LEAP Innovation Challenge Winner Creating a Pitch: Getting funded by talking instead of writing”
  • E4B trainee pitch sessions
  • Networking at Venture Cafe